Study Endpoints

Primary Endpoint

• Change from baseline in mean SBP during the last 6 hours of the dosing interval using ABPM after 14 weeks of treatment

Secondary Endpoints

• Change from baseline in DBP during the last 6 hours of the dosing interval using ABPM
• Changes from baseline in pulse pressure during the last 6 hours of the dosing interval using ABPM
• Changes from baseline in the 24-hour mean SBP and DBP using ABPM

References