Efficacy of MICARDIS^®

MICARDIS^® provides protection against the early morning surge in blood pressure and enduring, powerful 24-hour blood pressure control.

Early-morning blood pressure protection

During the early-morning hours, from 6 am to midday, it is well known that blood pressure rises if not adequately controlled and that the risk of cardiovascular events is at its highest.^1-3

Meta-analysis of five multicentre trials using ambulatory blood pressure monitoring to compare the antihypertensive efficacy of MICARDIS^®, losartan, valsartan and amlodipine showed that MICARDIS^® was significantly superior to losartan and valsartan in the reduction of systolic and diastolic blood pressure during this risky, early-morning period.

MICARDIS^® provided comparable blood pressure reduction to amlodipine during the morning period.⁴

MICARDIS^® provides powerful, consistent 24-hour blood pressure control

Studies have shown that MICARDIS^® was consistently more effective than ramipril for the reduction of mean diastolic blood pressure over 24 hours, as well as during the morning, daytime and evening periods. ^5,6

MICARDIS^® has also been proven to be more effective than ramipril at reducing blood pressure in the last 6 hours of the dosing interval. ^5,6

In trials comparing MICARDIS^® to losartan and valsartan, MICARDIS^® was superior to both agents in lowering systolic and diastolic blood pressure during this period.^7,8

References